Article
Two distinct chronic obstructive pulmonary disease (COPD) phenotypes are associated with high risk of mortality.
PloS one - 1 Jan 2012
Burgel Pierre-Régis, Paillasseur Jean-Louis, Peene Bernard, Dusser Daniel, Roche Nicolas, Coolen Johan, Troosters Thierry, Decramer Marc, Janssens Wim
Abstract excerpt
RATIONALE: In COPD patients, mortality risk is influenced by age, severity of respiratory disease, and comorbidities. With an unbiased statistical approach we sought to identify clusters of COPD patients and to examine their mortality risk. METHODS: Stable COPD subjects (n = 527) were classified using hierarchical cluster analysis of clinical, functional and imaging data. The relevance of this classification was...
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