Article

Detecting significantly recurrent genomic connections from simple and complex rearrangements in the cancer genome

2023-10-17

Abstract excerpt

The detection of somatic genetic alterations that recur across cancer genomes more than expected by chance has been a major goal of cancer genomics, as these alterations are enriched for “driver” events that promote cancer. Multiple methods have been developed to detect driver point mutations and copy-number variants, but methods to detect driver rearrangements have largely not been pursued. Unlike point mutations...

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Literature Corpus work: 249c14e6-d157-5bbd-b782-a84c661ee767
DOI: 10.1101/2023.10.13.561748

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