Article
Position-Dependent NMD Generates Diverse Protein Outcomes
2026-08-25
Abstract excerpt
Nonsense-mediated mRNA decay (NMD) is a translation-dependent mRNA decay pathway triggered by premature termination codons (PTCs). Although NMD is known to eliminate aberrant transcripts, how PTC position influences cell-to-cell heterogeneity in NMD and the resulting protein outputs remains unclear. Here, we used a single-cell NMD analysis system that quantifies cellular variability based on the GFP/mCherry fluore...
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Identifiers and source
- Literature Corpus work
- 23f7ca7d-e8cd-5b02-a4e4-9302e9e39256
- DOI
- 10.64898/2026.08.24.746594