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A ketogenic diet mitigates hippocampal astrogliosis in epileptic brain

2025-04-12

Abstract excerpt

The ketogenic diet (KD) is an established treatment for patients with medically intractable epilepsy and is chiefly characterized by high fat/low-carbohydrate intake and the production of ketone bodies (KB) such as β-hydroxybutyrate (BHB). However, after more than a century of clinical use, the mechanisms underlying its efficacy remain unclear. While prior investigations have examined the effects of the KD and its...

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Literature Corpus work
23d1d306-c0b7-5944-9f5b-30665aab7fff
DOI
10.1101/2025.04.11.647636
Open publication

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A ketogenic diet mitigates hippocampal astrogliosis in epileptic brainDOI 10.1101/2025.04.11.647636
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