Article

Gene Networks and Pathways for Plasma Lipid Traits via Multi-tissue Multi-omics Systems Analysis

2020-02-29

Abstract excerpt

Genome-wide association studies (GWAS) have implicated ∼380 genetic loci for plasma lipid regulation. However, these loci only explain 17-27% of the trait variance and a comprehensive understanding of the molecular mechanisms has not been achieved. In this study, we utilized an integrative genomics approach leveraging diverse genomic data from human populations to investigate whether genetic variants associated wi...

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Literature Corpus work: 23bb116f-f108-5c34-a7ca-653fc7cb1b36
DOI: 10.1101/2020.02.28.970368

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