Article

A <i>Trypanosoma brucei</i> ORFeome-based Gain-of-Function Library reveals novel genes associated with melarsoprol resistance

2019-11-20

Abstract excerpt

<h4>ABSTRACT</h4> Trypanosoma brucei is an early branching protozoan that causes Human and Animal African Trypanosomiasis. Forward genetics approaches are powerful tools for uncovering novel aspects of Trypanosomatid biology, pathogenesis, and therapeutic approaches against trypanosomiasis. Here we have generated a T. brucei ORFeome consisting of over 90% of the targeted genome and used it to make an inducible G...

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Literature Corpus work: 239785ba-a882-5705-8bc4-f3a604a07149
DOI: 10.1101/849042

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