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Chromosome-wide analysis of gene function by RNA interference in the african trypanosome.

Eukaryotic cell - 1 Sept 2006

Subramaniam Chandra, Veazey Paul, Redmond Seth, Hayes-Sinclair Jamie, Chambers Emma, Carrington Mark, Gull Keith, Matthews Keith, Horn David, Field Mark C

Abstract excerpt

Trypanosomatids of the order Kinetoplastida are major contributors to global disease and morbidity, and understanding their basic biology coupled with the development of new drug targets represents a critical need. Additionally, trypanosomes are among the more accessible divergent eukaryote experimental systems. The genome of Trypanosoma brucei contains 8,131 predicted open reading frames (ORFs), of which over...

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Identifiers

PMID: 16963636
DOI: 10.1128/EC.00141-06
PMCID: PMC1563588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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