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Article

Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes.

Nature protocols - 1 Jan 2015

Glover Lucy, Alsford Sam, Baker Nicola, Turner Daniel J, Sanchez-Flores Alejandro, Hutchinson Sebastian, Hertz-Fowler Christiane, Berriman Matthew, Horn David

Abstract excerpt

The ability to simultaneously assess every gene in a genome for a role in a particular process has obvious appeal. This protocol describes how to perform genome-scale RNAi library screens in bloodstream-form African trypanosomes, a family of parasites that causes lethal human and animal diseases and also serves as a model for studies on basic aspects of eukaryotic biology and evolution. We discuss strain...

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PMID: 25502887
DOI: 10.1038/nprot.2015.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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