Article

Genetic profiling of the isoprenoid and sterol biosynthesis pathways of Trypanosoma cruzi

2013-07-19

Abstract excerpt

<h4>Background: </h4> Sterols such as cholesterol, are important components of cellular membranes. But unlike mammalian cells, the main sterols found in the membranes of trypanosomes and fungi are ergosterol, and other 24-methyl sterols, which are required for growth and viability. In spite of this strict requirement, this group of organisms have evolved different strategies to produce and/or obtain sterols. Trypa...

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Literature Corpus work: aaed1d5e-15bc-5678-9ec3-dfa831de6366
DOI: 10.7287/peerj.preprints.44v1

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