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Article

The Genome of the African Trypanosome <i>Trypanosoma brucei</i>

14 Jul 2005

Abstract excerpt

African trypanosomes cause human sleeping sickness and livestock trypanosomiasis in sub-Saharan Africa. We present the sequence and analysis of the 11 megabase-sized chromosomes of Trypanosoma brucei. The 26-megabase genome contains 9068 predicted genes, including approximately 900 pseudogenes and approximately 1700 T. brucei-specific genes. Large subtelomeric arrays contain an archive of 806 variant surface...

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PMID: 16020726
DOI: 10.1126/science.1112642

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