Article

Homologous Recombination Deficiency Among Patients with Germline or Somatic non-BRCA1/2 Homologous Recombination Repair Gene Variations

2025-04-28

Abstract excerpt

<title>Abstract</title> <p>This study examined the relationship between homologous recombination deficiency (HRD) and variations in non-<italic>BRCA1/2</italic> homologous recombination repair (HRR) genes. 27.3% (132/483) of the patients with ovarian, breast, endometrial, prostate, and pancreatic cancers carrying non-<italic>BRCA1/2</italic> HRR variations were HRD+. Germline mutations were associated with signif...

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Literature Corpus work: 2394949d-8611-53c2-9b21-664d5e0abaf5
DOI: 10.21203/rs.3.rs-5538972/v1

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