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Homologous recombination deficiency gene panel analysis results in synchronous endometrial and ovarian cancers.

Revista da Associacao Medica Brasileira (1992) - 1 Jan 2024

Kazanci Ferah, Çelik Zerrin Yılmaz, Polat Mert, Karademir Ferhat, Erdem Ozlem, Şahin Feride İffet, Onan Mehmet Anil

Abstract excerpt

OBJECTIVE: The objective of this study was to analyze the genetic alterations of tumors within the scope of the homologous recombination deficiency gene panel in patients diagnosed with synchronous endometrial ovarian cancer who have been followed for over 5 years using next-generation sequencing. METHODS: DNA was isolated from the patient's formalin-fixed, paraffin-embedded tissue blocks. Next-generation...

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Aged
Endometrial Neoplasms
High-Throughput Nucleotide Sequencing
Homologous Recombination
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasms, Multiple Primary

Ovarian Neoplasms

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Identifiers

PMID: 39356959
DOI: 10.1590/1806-9282.20240534
PMCID: PMC11444207

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