Article
Genetic evidence for lifestyle and cardiometabolic factors on the risk of aortic aneurysms: A comprehensive Mendelian randomization study.
Atherosclerosis - 1 Oct 2024
Liu Chenxi, Peng Jia, Liu Yubo, Peng Yi, Ma Qilin
Abstract excerpt
BACKGROUND AND AIMS: Aortic aneurysm (AAs) is a chronic and severe aortic disease, which is extremely life-threatening due to its delayed diagnosis and a high risk of rupture. In current studies, the association between lifestyle and metabolic factors remains controversial given the complexity of pathogenesis and progression in AAs. Consequently, more reliable and robust evidence should be provided. METHODS:...
Topics
- Humans
- Mendelian Randomization Analysis
- Genome-Wide Association Study
- Aortic Aneurysm
- Life Style
- Genetic Predisposition to Disease
- Cardiometabolic Risk Factors
- Risk Assessment
- Triglycerides
- Risk Factors