Article

Control of Ribosomal RNA Synthesis by Hematopoietic Transcription Factors

2022-01-22

Abstract excerpt

<h4>SUMMARY</h4> Ribosomal RNAs (rRNAs) are the most abundant cellular RNAs, and their synthesis from rDNA repeats by RNA Polymerase I accounts for the bulk of all transcription. Despite substantial variation in rRNA transcription rates across cell types, little is known about cell-type-specific factors that bind rDNA and regulate rRNA transcription to meet tissue-specific needs. Using hematopoiesis as a model sy...

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Literature Corpus work: 2372e1df-4abc-5d55-987a-7d712f0cfd34
DOI: 10.1101/2022.01.21.476118

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