Article

The RNA-binding landscape of HAX1 protein indicates its involvement in ribosome biogenesis and translation

2022-01-15

Abstract excerpt

<h4>ABSTRACT</h4> HAX1 is a human protein with no known homologues or structural domains, mutations in which cause severe congenital neutropenia through mechanisms that are poorly understood. Previous studies reported RNA-binding capacity of HAX1, but the role of this binding in physiology and pathology remains unexplained. Here we report transcriptome-wide characterization of HAX1 RNA targets using RIP-seq and C...

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Literature Corpus work: 527a1ed0-6394-5979-987b-4dcf059a2bd8
DOI: 10.1101/2022.01.14.476349

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