Article
The sub-nucleolar localization of PHF6 defines its role in rDNA transcription and early processing events.
European journal of human genetics : EJHG - 1 Oct 2016
Todd Matthew A M, Huh Michael S, Picketts David J
Abstract excerpt
Ribosomal RNA synthesis occurs in the nucleolus and is a tightly regulated process that is targeted in some developmental diseases and hyperactivated in multiple cancers. Subcellular localization and immunoprecipitation coupled mass spectrometry demonstrated that a proportion of plant homeodomain (PHD) finger protein 6 (PHF6) protein is localized within the nucleolus and interacts with proteins involved in...
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