Article

A multidimensional atlas of human glioblastoma organoids reveals highly coordinated molecular networks and effective drugs

2023-01-24

Abstract excerpt

Recent advances in the genomics of glioblastoma (GBM) led to the introduction of molecular neuropathology but failed to translate into treatment improvement. This is largely attributed to the genetic and phenotypic heterogeneity of GBM, which are considered the major obstacle to GBM therapy. Here, we use advanced human GBM organoid (LEGO: L aboratory E ngineered G lioblastoma O rganoid) and provide an unpreced...

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Literature Corpus work: 22ec019e-621d-5345-bd10-28cca7a836eb
DOI: 10.1101/2023.01.24.525374

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