Article

Multi-omics and Pharmacological Characterization of Patient-derived Glioma Cell Lines

2023-02-21

Abstract excerpt

Glioblastoma (GBM) is the most common brain tumor and is currently incurable. Primary GBM cultures are widely used tools for screening potentially therapeutic drugs; however, there is a lack of genomic and pharmacological characterization of these primary GBM cultures. Here, we collected 52 patient-derived glioma cell (PDGC) lines and characterized them through whole- genome sequencing (WGS), RNA-seq, and drug res...

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Literature Corpus work: 9296c126-567e-5cb9-92d1-b69db190f987
DOI: 10.1101/2023.02.20.529198

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