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Article

New antigens for a multicomponent blood-stage malaria vaccine

30 Jul 2014

Abstract excerpt

An effective blood-stage vaccine against Plasmodium falciparum remains a research priority, but the number of antigens that have been translated into multicomponent vaccines for testing in clinical trials remains limited. Investigating the large number of potential targets found in the parasite proteome has been constrained by an inability to produce natively folded recombinant antigens for immunological studies....

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PMID: 25080477
DOI: 10.1126/scitranslmed.3008705

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