Article

An atlas of genetic variation for linking pathogen-induced cellular traits to human disease

2017-10-16

Abstract excerpt

<h4>Summary</h4> Genome-wide association studies (GWAS) have identified thousands of genetic variants associated with disease. To facilitate moving from associations to disease mechanisms, we leveraged the role of pathogens in shaping human evolution with the Hi-HOST Phenome Project (H2P2): a catalog of cellular GWAS comprised of 79 phenotypes in response to 8 pathogens in 528 lymphoblastoid cell lines. Seventeen...

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Literature Corpus work: 22d79e5a-7fc5-5401-b71c-27ee98a46a81
DOI: 10.1101/202325

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