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Poly-γ-Glutamic Acid/Alum Adjuvanted pH1N1 Vaccine-Immunized Aged Mice Exhibit a Significant Increase In Vaccine Efficacy With a Decrease in Age-Associated CD8+ T Cell Proportion in Splenocytes

2021-11-12

Abstract excerpt

<h4>Background: </h4> Highly contagious respiratory diseases caused by viral infections are a constantly emerging threat, particularly the elderly with the higher risk of developing serious complications. Vaccines are the best strategy for protection against influenza-related diseases. However, the elderly has lower vaccine efficacy and the age-driven decline of the influenza vaccine efficacy remains unresolved. I...

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Literature Corpus work
22a64f52-f7d8-5fe4-8bb2-6e6df21c51a4
DOI
10.21203/rs.3.rs-1035774/v1
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Poly-γ-Glutamic Acid/Alum Adjuvanted pH1N1 Vaccine-Immunized Aged Mice Exhibit a Significant Increase In Vaccine Efficacy With a Decrease in Age-Associated CD8+ T Cell Proportion in SplenocytesDOI 10.21203/rs.3.rs-1035774/v1
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