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Article

Identification and Characterization of Stimulator of Interferon Genes As a Robust Adjuvant Target for Early Life Immunization

11 Dec 2017

Abstract excerpt

Immunization is key to preventing infectious diseases, a leading cause of death early in life. However, due to age-specific immunity, vaccines often demonstrate reduced efficacy in newborns and young infants compared to adults. Here we combined in vitro and in vivo approaches to identify adjuvant candidates for early life immunization. We employed newborn and adult bone marrow-derived dendritic cells (BMDCs) to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29312305
DOI: 10.3389/fimmu.2017.01772

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