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Article

Broad heterologous protection against Influenza A viruses by an adjuvant-free modular mucosal T-cell vaccine platform.

2026-06-08

Abstract excerpt

<title>Abstract</title> <p>Rapid antigenic evolution of Influenza A viruses (IAVs) enables their escape from strain-specific vaccine immunity and underscores the need for broadly protective strategies. Here, we describe a modular, adjuvant-free mucosal vaccine platform that elicits potent and cross-protective T cell immunity. The approach uses overlapping CD4+ and CD8+ epitope-dense regions from the consensus IAV...

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Identifiers and source

Literature Corpus work
09c207e2-3969-5735-bdef-53c73560ad8e
DOI
10.21203/rs.3.rs-9920926/v1
Open publication

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Broad heterologous protection against Influenza A viruses by an adjuvant-free modular mucosal T-cell vaccine platform.DOI 10.21203/rs.3.rs-9920926/v1
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