Article

Antiviral CD4 <sup>+</sup> T and myeloid cell responses to influenza vaccines are attenuated in older adults

2025-05-06

Abstract excerpt

<h4>ABSTRACT</h4> Recent influenza vaccine formulations have improved the magnitude of B-cell antibody responses in older adults; however, older adults remain significantly at risk for severe influenza-related illness. Although antibodies are an important metric of vaccine effectiveness, they only represent one aspect of the immune response. In this study, we combined in vitro and ex vivo assays with human sample...

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Literature Corpus work: b5eb4c21-9b60-5326-85d4-00f7716ece57
DOI: 10.1101/2025.04.30.651528

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