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LiteVax-adjuvanted influenza vaccine induces transient interferon-driven innate activation and accelerates early IgG3 responses in older adults

2026-08-03

Abstract excerpt

<title>Abstract</title> <p>Vaccine immunogenicity declines with age due to immunosenescence, underscoring the need for improved adjuvants. LiteVax Adjuvant (LVA), a squalane-in-water emulsion containing carbohydrate fatty-acid monosulphate esters, has shown potential to enhance influenza vaccine responses, but its mechanisms in humans remain unclear. We performed a longitudinal systems vaccinology study in 56 you...

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Literature Corpus work
a3ea9c6e-b558-520f-9f42-478caaf16bca
DOI
10.21203/rs.3.rs-10356158/v1
Open publication

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LiteVax-adjuvanted influenza vaccine induces transient interferon-driven innate activation and accelerates early IgG3 responses in older adultsDOI 10.21203/rs.3.rs-10356158/v1
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