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Broad heterologous protection against Influenza A viruses by an adjuvant-free modular mucosal T-cell vaccine platform

2026-03-31

Abstract excerpt

Rapid antigenic evolution of Influenza A viruses (IAVs) enables their escape from strain-specific vaccine immunity and underscores the need for broadly protective strategies. Here, we describe a modular, adjuvant-free mucosal vaccine platform that elicits potent and cross-protective T cell immunity. The approach uses overlapping CD4+ and CD8+ epitope-dense regions from the consensus IAV M1 and NP proteins, identif...

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Literature Corpus work
c9d5e344-41e0-50db-9656-e80c3ee6478e
DOI
10.64898/2026.03.29.715080
Open publication

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Broad heterologous protection against Influenza A viruses by an adjuvant-free modular mucosal T-cell vaccine platformDOI 10.64898/2026.03.29.715080
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