Article

The conserved zinc-finger protein GTSF1 helps PIWI proteins achieve their full catalytic potential

2021-05-04

Abstract excerpt

Argonaute proteins use nucleic acid guides to find and bind specific DNA or RNA target sequences. Argonaute proteins can be found in all kingdoms of life, and play diverse biological functions including genome defense, gene regulation, and chromosome partitioning. Many Argonautes retain their ancestral endoribonuclease activity, cleaving the phosphodiester bond between target nucleotides t10 and t11. In animals, a...

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Literature Corpus work: 2297c709-156a-546a-970f-b106601a34ab
DOI: 10.1101/2021.05.04.442675

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