Article

Transcriptional signatures of heroin intake and seeking throughout the brain reward circuit

2023-01-12

Abstract excerpt

Opioid use disorder (OUD) looms as one of the most severe medical crises currently facing society. More effective therapeutics for OUD requires in-depth understanding of molecular changes supporting drug-taking and relapse. Recent efforts have helped advance these aims, but studies have been limited in number and scope. Here, we develop a brain reward circuit-wide atlas of opioid-induced transcriptional regulation...

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Literature Corpus work: 225fee07-b0cb-5bd0-a244-4250e06490ab
DOI: 10.1101/2023.01.11.523688

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