Article

Epigenetic signals that direct cell type specific interferon beta response in mouse cells

2022-02-27

Abstract excerpt

The antiviral response induced by type I interferon (IFN) via the JAK-STAT signaling cascade activates hundreds of IFN-stimulated genes (ISGs). While this response occurs essentially in all human and mouse tissues it varies between different cell types. However, the linkage between the underlying epigenetic features and the ISG pattern of a given cell is not well understood. We mapped ISGs, binding sites of the ST...

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Literature Corpus work: 222fb76d-2124-5092-9be8-7e0fc4f1032b
DOI: 10.1101/2022.02.26.481127

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