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Epigenetic and transcriptional control of interferon-β

23 Jul 2021

Abstract excerpt

The three classes of interferons (IFNs) share the ability to inhibit viral replication, activating cell transcriptional programs that regulate both innate and adaptive responses to viral and intracellular bacterial challenge. Due to their unique potency in regulating viral replication, and their association with numerous autoimmune diseases, the tightly orchestrated transcriptional regulation of IFNs has long...

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PMID: 34297037
DOI: 10.1084/jem.20210039

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