Article

Single-cell copy number alteration signature analysis reveals masked patterns and potential biomarkers for cancer

2025-03-04

Abstract excerpt

<h4>Summary</h4> Copy number alteration (CNA) is a major type of cancer genome alteration that drives cancer progression. CNA signature analysis can reveal underlying etiology and provide biomarkers for cancer treatment, and existing CNA signature analyzes are all performed using bulk tissue samples. However CNA usually affect large proportion of genome, and the CNA profile of bulk sample does not reflect the act...

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Literature Corpus work: 21ffae3d-7719-5a4a-bf94-636506ce8a2f
DOI: 10.1101/2025.03.02.641098

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