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Article

Single-cell profiling of the copy-number heterogeneity in colorectal cancer.

Chinese medical journal - 20 Mar 2023

Song Shiyu, Feng Lin, Xi Kexing, Sun Zhigang, Kong Deyang, Luo Zhenkai, Pei Wei, Zhang Haizeng

Abstract excerpt

BACKGROUND: With functionally heterogeneous cells, tumors comprise a complex ecosystem to promote tumor adaptability and evolution under strong selective pressure from the given microenvironment. Diversifying tumor cells or intra-tumor heterogeneity is essential for tumor growth, invasion, and immune evasion. However, no reliable method to classify tumor cell subtypes is yet available. In this study, we...

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Identifiers

PMID: 36914941
DOI: 10.1097/CM9.0000000000002469
PMCID: PMC10129169

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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