Article

Direct long-read RNA sequencing uncovers functional variation affecting transcript production and RNA modifications

2024-07-08

Abstract excerpt

<title>Abstract</title> <p>The production of multiple transcripts per gene is a process regulated by inherited genetic variants and epitranscriptomic modifications, and plays a prominent role in modulating complex traits and diseases. To simultaneously characterize the effect of genetic variants on transcript abundance and N6-methyladenosine (m6A) modifications, we produced long-read native poly(A) RNA-seq data f...

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Literature Corpus work: 21e36c1b-8258-56e8-8976-bbd1dc8d264e
DOI: 10.21203/rs.3.rs-4613444/v1

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