Article

Nanopore-based native RNA sequencing of human transcriptomes reveals the complexity of mRNA modifications and crosstalk between RNA regulatory features

2024-07-16

Abstract excerpt

The identification and functional characterization of chemical modifications on an mRNA molecule, in particular N 6 -methyladenosine (m 6 A) modification, significantly broadened our understanding of RNA function and regulation. While interactions between RNA modifications and other RNA features have been proposed, direct evidence showing correlation is limited. Here, using Oxford Nanopore long-read direct RNA s...

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Literature Corpus work: 39c216ab-8e1d-55b7-80e7-846087a89474
DOI: 10.1101/2024.07.11.603105

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