Article

Direct long-read RNA sequencing uncovers functional variation affecting transcript production and RNA modifications

2026-05-12

Abstract excerpt

<title>Abstract</title> <p>The production of multiple transcripts per gene is a process regulated by inherited genetic variants and epitranscriptomic modifications, and plays a prominent role in modulating complex traits and diseases. To simultaneously characterize the effect of genetic variants on transcript abundance and N6-methyladenosine (m⁶A) modifications, we produced long-read native poly(A) RNA-seq data f...

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Literature Corpus work: fc52e7c7-1adc-506c-84d6-58f766dd70bc
DOI: 10.21203/rs.3.rs-4613444/v2

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