Article

Genetic Depletion of Amylin/Calcitonin Receptors Improves Memory and Learning in Transgenic Alzheimer’s Disease Mouse Models.

2021-05-19

Abstract excerpt

<title>Abstract</title> <p>Based upon its interactions with amyloid β peptide (Aβ), the amylin receptor, a Class B G protein-coupled receptor (GPCR), is a potential modulator of Alzheimer’s disease (AD) pathogenesis. However, past pharmacological approaches have failed to resolve whether activation or blockade of this receptor would have greater therapeutic benefit. To address this issue, we generated compound mi...

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Literature Corpus work: 21cb754d-8254-5bda-aba7-20ae58479876
DOI: 10.21203/rs.3.rs-515476/v1

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Genetic Depletion of Amylin/Calcitonin Receptors Improves Memory and Learning in Transgenic Alzheimer’s Disease Mouse Models.DOI 10.21203/rs.3.rs-515476/v1Read

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