Article

Role of the Sirt6/Hmgb1 pathway in neuroinflammation of Sleep deprivation-induced depressed mice

2023-12-06

Abstract excerpt

Many depressed patients exhibit sleep disorders, which in turn are a driver of the onset of depression. There is substantial evidence that neuroinflammation plays a key role in the pathophysiology and treatment of depression. Here, we investigated the mechanisms by which sleep deprivation (SD) induced anxiety-depressive-like behaviors in mice and the role of neuroinflammation in it. Adult male C57BL/6J mice were s...

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Literature Corpus work: 20dc1548-611d-599d-b0fb-345af1e36359
DOI: 10.21203/rs.3.rs-3687315/v1

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