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Article

A novel two-hit insomnia and inflammation rodent model of depressive-like behaviors

2024-08-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Systemic inflammation and insomnia often co-occur in patients with depression. However, there is no suitable animal model to investigate the relationship between inflammation, sleep deprivation (SD), and depression. <h4>Methods</h4> To model interactions between insomnia, inflammation, and depression, we developed a novel “two-hit” rodent model of depressive-like behaviors usi...

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Literature Corpus work
e1edea7c-0c99-5179-9477-439d0c6b3a60
DOI
10.1101/2024.08.01.24311351
Open publication

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A novel two-hit insomnia and inflammation rodent model of depressive-like behaviorsDOI 10.1101/2024.08.01.24311351
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