Article

Inflammation from Sleep Fragmentation Starts in the Periphery Rather than Brain in Male Mice

2023-02-13

Abstract excerpt

Obstructive sleep apnea is increasing worldwide, leading to disordered sleep patterns and inflammatory responses in brain and peripheral tissues that predispose individuals to chronic disease. Pro-inflammatory cytokines activate the inflammatory response and are normally regulated by glucocorticoids secreted from adrenal glands. However, the temporal dynamics of inflammatory responses and hypothalamic-pituitary-ad...

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Literature Corpus work: 5eb7801c-083e-5d29-bc10-de42c6658e99
DOI: 10.21203/rs.3.rs-2544592/v1

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