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Design, infectability, and transcriptomic analysis of transregionally differentiated and scalable lung organoids derived from adult bronchial cells

2024-07-03

Abstract excerpt

The lung is a primary target for many lethal respiratory viruses, leading to significant global mortality. Current organoid models fail to completely mimic the cellular diversity and intricate tubular and branching structures of the human lung. Lung organoids derived from adult primary cells have so far only included cells from the input cell region, proximal or distal. Existing models are expensive. They often re...

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Literature Corpus work
a6806bbf-3d6b-5005-ac92-4645d14b5d57
DOI
10.1101/2024.07.02.601655
Open publication

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Design, infectability, and transcriptomic analysis of transregionally differentiated and scalable lung organoids derived from adult bronchial cellsDOI 10.1101/2024.07.02.601655
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