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Impact of cell culture model systems on SARS-CoV-2 and MERS-CoV infection dynamics and antiviral responses

2025-02-27

Abstract excerpt

Cell cultures are widely used to study infectious respiratory diseases and to test therapeutics; however, they do not faithfully recapitulate the architecture and complexity of the human respiratory tract. Lung organoids have emerged as an alternative model that partially overcomes this key disadvantage. Lung organoids can be cultured in various formats that offer potential for studying highly pathogenic viruses....

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Literature Corpus work
0f6afe68-74cd-54e1-8857-f55827efcabd
DOI
10.1101/2025.02.24.639954
Open publication

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