Article

Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19

2020-10-18

Abstract excerpt

<h4>Summary</h4> SARS-CoV-2, the virus responsible for COVID-19, causes widespread damage in the lungs in the setting of an overzealous immune response whose origin remains unclear. We present a scalable, propagable, personalized, cost-effective adult stem cell-derived human lung organoid model that is complete with both proximal and distal airway epithelia. Monolayers derived from adult lung organoids (ALOs), pr...

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Literature Corpus work: cb756f9a-43e8-518b-9452-0e1e237141d5
DOI: 10.1101/2020.10.17.344002

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