Article

Development of robust antiviral assays using relevant apical-out human airway organoids

2024-01-04

Abstract excerpt

While breakthroughs with organoids have emerged as next-generation in vitro tools, standardization for drug discovery remains a challenge. This work introduces human airway organoids with reversed biopolarity (AORBs), cultured and analyzed in a high-throughput, single-organoid-per-well format, enabling milestones towards standardization. AORBs exhibit a spatio-temporally stable apical-out morphology, facilitating...

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Literature Corpus work: 46ba9d7c-c14a-5067-864d-8550a081925f
DOI: 10.1101/2024.01.02.573939

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