Article

CD47 antisense oligonucleotide treatment attenuates obesity and its-associated metabolic dysfunction

2023-02-13

Abstract excerpt

<title>Abstract</title> <p>Previous study from our lab has revealed a new role of CD47 in regulating adipose tissue function, energy homeostasis and the development of obesity and metabolic disease in CD47 deficient mice. In this study, the therapeutic potential of an antisense oligonucleotide (ASO) targeting to CD47 in obesity and its-associated complications was determined in two obese mouse models (diet induce...

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Literature Corpus work: 2034ee3b-0d5b-5398-9c4c-a772a6aefa75
DOI: 10.21203/rs.3.rs-2362549/v2

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