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Article

The CB1 receptor antagonist rimonabant reverses the diet-induced obesity phenotype through the regulation of lipolysis and energy balance.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Sept 2005

Jbilo Omar, Ravinet-Trillou Christine, Arnone Michèle, Buisson Isabelle, Bribes Estelle, Péleraux Annick, Pénarier Géraldine, Soubrié Philippe, Le Fur Gérard, Galiègue Sylvaine, Casellas Pierre

Abstract excerpt

We investigated the molecular events involved in the long-lasting reduction of adipose mass by the selective CB1 antagonist, SR141716. Its effects were assessed at the transcriptional level both in white (WAT) and brown (BAT) adipose tissues in a diet-induced obesity model in mice. Our data clear...

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Source

Identifiers

PMID: 16009704
DOI: 10.1096/fj.04-3177fje

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16009704-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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