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Article

Phenotypic Discovery of SB1501, an Anti-obesity Agent, through Modulating Mitochondrial Activity.

ChemMedChem - 8 Apr 2021

Jo Ala, Kim Mingi, Kim Jong In, Ha Jaeyoung, Hwang Yoon Soo, Nam Hyunsung, Hwang Injae, Kim Jae Bum, Park Seung Bum

Abstract excerpt

Obesity has become a pandemic that threatens the quality of life and discovering novel therapeutic agents that can reverse obesity and obesity-related metabolic disorders are necessary. Here, we aimed to identify new anti-obesity agents using a phenotype-based approach. We performed image-based high-content screening with a fluorogenic bioprobe (SF44), which visualizes cellular lipid droplets (LDs), to identify...

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PMID: 33538065
DOI: 10.1002/cmdc.202100062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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