Article

Mechanistic insights into the deleterious role of nasu-hakola disease associated TREM2 variants

2019-07-17

Abstract excerpt

Recently, critical roles of genetic variants in Triggering Receptor Expressed on Myeloid cells 2 (TREM2) for myeloid cells to Alzhimer’s disease have been aggressively highlighted. However, little studies focused to the deleterious role of Nasu-Hakola disease (NHD) associated TREM2 variants. In order to get insights into the contributions of these variants in neurodegeneration, we investigated the influences of th...

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Literature Corpus work: 201b8bca-d850-52fb-943b-89fec85e2a62
DOI: 10.1101/705608

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