Article

Signaling pathway screening platforms are an efficient approach to identify therapeutic targets in precision-medicine oriented early phase clinical trials

2018-01-26

Abstract excerpt

Precision medicine aims to tailor cancer therapies to target specific tumorpromoting aberrations. For tumors that lack actionable drivers, extensive molecular characterization and pre-clinical drug efficacy studies will be required to match patients with the appropriate targeted therapy. A cell line maintained at low passage and a patient-derived xenograft model (PDX) were generated using a fresh biopsy from a pat...

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Literature Corpus work: 1fc4e5de-ec6f-5e35-8a0f-5e5c6033f090
DOI: 10.1101/254342

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