Article
Signaling network assessment of mutations and copy number variations predict breast cancer subtype-specific drug targets.
Cell reports - 17 Oct 2013
Zaman Naif, Li Lei, Jaramillo Maria Luz, Sun Zhanpeng, Tibiche Chabane, Banville Myriam, Collins Catherine, Trifiro Mark, Paliouras Miltiadis, Nantel Andre, O'Connor-McCourt Maureen, Wang Edwin
Abstract excerpt
Individual cancer cells carry a bewildering number of distinct genomic alterations (e.g., copy number variations and mutations), making it a challenge to uncover genomic-driven mechanisms governing tumorigenesis. Here, we performed exome sequencing on several breast cancer cell lines that represe...
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