Article

Deficits in Skilled Motor and Auditory Learning in a Rat Model of Rett Syndrome

2020-09-02

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Rett Syndrome is an X-linked neurodevelopmental disorder caused by a mutation in the gene <italic>MECP2</italic>. Individuals with Rett Syndrome display developmental regression at an early age, and develop a range of motor, auditory, cognitive and social impairments. Several studies have successfully modeled some aspects of dysfunction and Rett Syndrome-like ph...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1fab8f98-371d-5387-b284-26e8e922bb05
DOI: 10.21203/rs.3.rs-31477/v3

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Deficits in Skilled Motor and Auditory Learning in a Rat Model of Rett SyndromeDOI 10.21203/rs.3.rs-31477/v3Read

Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome.Semantic proximity Read

Motor, Somatosensory, Viscerosensory and Metabolic Impairments in a Heterozygous Female Rat Model of Rett Syndrome.Semantic proximity Read

Level of purposeful hand function as a marker of clinical severity in Rett syndrome.Semantic proximity Read

The GAIRS Checklist: A Useful Global Assessment Tool In Patients With Rett SyndromeSemantic proximity Read

Early motor phenotype detection in a female mouse model of Rett syndrome is improved by cross-fostering.Semantic proximity Read

Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome.Semantic proximity Read

The first mecp2-null zebrafish model shows altered motor behaviors.Semantic proximity Read

Deficient Purposeful Use of Forepaws in Female Mice Modelling Rett Syndrome.Semantic proximity Read

Early environmental enrichment moderates the behavioral and synaptic phenotype of MeCP2 null mice.Semantic proximity Read

Touchscreen learning deficits in Ube3a, Ts65Dn and Mecp2 mouse models of neurodevelopmental disorders with intellectual disabilities.Semantic proximity Read

Deleting <i>Mecp2</i> from the entire cerebellum rather than its neuronal subtypes causes a delay in motor learning in miceSemantic proximity Read

Specific mutations in methyl-CpG-binding protein 2 confer different severity in Rett syndrome.Semantic proximity Read